Impact of Prenatal Stress on brain ageing

Fetal programming, undernutrition and stress

 

Mission:
 Slowing brain ageing and susceptibility to
 age-associated diseases: Early programming 
of pathways and genes and late 
interventional targets.

 

Committed to healthy brain ageing
 from the very beginning

Grandma and Child: Fetal programming, stress, undernutrition and glucocorticoide

A healthy brain is a major determinant of good life-long health. Human epidemiological and animal studies indicate that in addition to life style and genetic factors, environmental influences in prenatal life have a major impact on brain ageing and age-associated brain disorders. Our consortium consists of leading European and US-American neuroscientists, physiologists, obstetricians, developmental psychologists and innovative biotech companies.


human-brain-smallOur project will determine structural and functional indicators of brain age. We examine to what extent prenatal stress, i.e. maternal stress, glucocorticoid treatment or malnutrition, mediate premature brain ageing and susceptibility to age-associated brain disorders such as cognitive decline and stroke. We dissect mechanisms and pharmacological interventions which may be used in elderly people. Information obtained will allow identification of people at risk for premature brain ageing and offer therapeutic interventions.

 

 

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schwab

Project Coordinator

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Matthias Schwab, MD

Department of Neurology

Jena University Hospital

Erlanger Allee 101

07747 Jena

Germany

Phone: 0049 3641 9 323 486

This email address is being protected from spambots. You need JavaScript enabled to view it.

kroegel n

Project Manager

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Nasim Kroegel, M.Sc.

Department of Neurology

Jena University Hospital

Erlanger Allee 101

07747 Jena

Germany

Phone: 0049 3641 9 323 409

This email address is being protected from spambots. You need JavaScript enabled to view it.